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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3b52b6e037dac78812f66a9428e67212551190616dc3043f784954cf3068406' 
  AND token = 'in9Z4gdMvCO5Wiyc6daybHAAzeGqNvIvmQ0CCRRu9g8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}