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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad539c72d40456167a2e73b6755e6e1594e9c711d8389f91c4fcc5a5242c8968' 
  AND token = 'WiZg9WBYMaMHNSXSYiVPkKKYAu3AElqTGRE1AXWTbWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}