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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f5964985bc2c9fbba29d501df0ee287ea858155c7e18c8c6ec0aed98ecdc681' 
  AND token = 'UxfmBpY6sV2LVkNsnSAzMIi1O11+AD/wb7V4U+BYDjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}