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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a234460a73c26f7e2c4b49e46494ff2f086fbc6bc79f2bea202f5aaa4e6a672' 
  AND token = 'ms0DN82VBoZk8R9XvuiHxJLUazjZkxJnUSOWG3K3X3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}