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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '124417f3b9ce23ed0cb2ead876f5364f68e53a24f6c442678561dd00c6648534' 
  AND token = 'JRzKIiK8Y6fH0IneTHsZoxx++1mHT11o5F80tkCJAkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}