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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c15ae8f7edbf317cc9f1f73088a36990383b8b96bcf9d27e69243869a8d9a79' 
  AND token = 'xf3Yex4YsAkhucGFiUMQzDUZJ5pgUzQDTiQC2NY3x6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}