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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3bed40f8f763be7164136794d0029f092353c2f04ba1b9d8fe235658f1ed535' 
  AND token = '21ZoY+hT1dtrx06bJhns15sHQd1KuZUI2fQQJ0YzlaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}