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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38e99a779ecde76486bd20eb5441c25421117dac663382d5376c5213a313a5de' 
  AND token = 'm/f03Wn+2anqbsBrGUATcXxwZrJ9vYARUeAxH9XvK5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}