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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2171634fd729072f43d7c7576cd7c36b925222b661e2da91fa10f4435b9ce2b6' 
  AND token = 'HLmFkc8ueH+r6rNibu5skia2oMwVD8dSSgRslU96qy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}