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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b285865ffc8f62065dc933bc9023db5d24ac1f649f47b738fb35631aa0fc162' 
  AND token = '2ZJRA2JDxzfFZph5rdwF8IVu9WxCDdSuxAidqXTkXO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}