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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea33403ed57b2c3e393a0e6865313b28161abef8a3fa2baac8e2dc7e73c9d961' 
  AND token = '2xsAUcHAU6qLWQMpTknhkKQ1TgwMrcZ4A/ixRwWr4wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}