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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d209648e68184fbe4a772c07fa028000fa0a565244e7395cbb14603552204c1' 
  AND token = 'mKnrslMXE48yz2B2+NsmPk+V2ugOGe5tLXVtjLrSUe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}