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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09d6dcfa476bea760a803b7f4478a2e557c39299d441d8d6f25a69fcfc8f3a9b' 
  AND token = '5xlRAejVhWOq4jApKkH/bfXNJK539FrYxFnY523NESA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}