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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fc8c0b44917e5dcb9296ea5669e953ce0c9afca9be4ee581bab96bcb22b3c54' 
  AND token = 'LYfNV/urZ1lp0CGADVKsKDTNqGpl5lXZyAj/eX+mwE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}