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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54fc2b5011f3dde00c8b1df541cbe0eff4dad26c341ffe48030ca6c287f1663c' 
  AND token = 'LImcp+McWZKk+teUgkMbot18HeKc59hFs0XVZ0TO4n8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}