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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6df0b600c3284adb19a027650612de5f52562fe1aa2ec26685834086114bee38' 
  AND token = 'iibSP9QgwSa9vDXVoFD+mnFE9pZeSzDzOhqEtmnnlyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}