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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '724c90299bea384426186dc1db5fcafe138abb0b58199b5cb90ad6f600e28795' 
  AND token = 'kKeOBO3HjEi4zSe2tcuPwuKnZiGt8/WGaUsBibLb7lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}