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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e25d7266b75e83597c92e5dd8f25bda26faa32ecb88041554a1ffb297a42f7ba' 
  AND token = '51Xstb+XC2rO48qFbMEaUU5MfFICruWB2tCO0/eN8fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}