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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a6395d44d139efeb44e0d44281f803ab8b48c5d64167bfb74b46bd0eb7ba250' 
  AND token = 'CMFiprPnHDymQ+KCqvPmlun5+zguI6R2KkQe1GerXuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}