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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef6f501ae0ee289f21278e5e0cb7b0f51ae24f9b8031781536975db6df8f102' 
  AND token = '2sIK4xQ/SaNeJH7DqKJoTers/WYFRSzNv5xm0qYrgIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}