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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11f45e93e97da293623b573398c306d0fbc0d088ff15765f5b659e2d63d4bd44' 
  AND token = 'T1rDmg3Hv9E6rUT8oNglHYFPnY405BwJDQyE6f6AAVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}