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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88c163851a168e3505e54bb7270883fb3f01b3cf00f2c73a149e56c6ab89793e' 
  AND token = 'XJxWx3VE32Jc0xyk3wmvBziWtGzA/LUTScg4bqXIWzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}