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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b3dfcdfe559179bea94e0103320089875d89b6437c642b6704aac1ecdcc3f0' 
  AND token = 'F2j1DeHxaWR/PGcfpRlbMLSS6iG2U3uaGA7422o7MbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}