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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c50746b800987f2feb884a6b2fecccb73db27755fa78430c3632ef9f4d24ed9' 
  AND token = 'ddZaOZpGmA8PXOHsI2mGGN7Tf1dw5qbH0I+NCGkhuww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}