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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a04fdca39b02b004286b99ab046e1196a034002b830892bcf35df9e3affc17b1' 
  AND token = 'MDG21xb07mOBOyd5s24/roz17B/mxk2pgWOMkYeKlpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}