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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19a40744168c283e46e922d162355a32c89a4c7ac7b7d5a4924e1d4ccc387c77' 
  AND token = 'NfggRm6NDQ47Kl21UU0JEAqcKr6iu23yA8ncGVWgaCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}