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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8be4a235418d20db63ff4e8a8d069d2cb18f419af66749d487c242b09d90196' 
  AND token = 'w8OrlB8HFEn/upi/rcTJzq6orJGV3B0WyA5yd2+Bxdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}