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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cc82c6cd606cd4984b08856819b0a75b8bd160fe4a0c1b13c6c6d03aebafd23' 
  AND token = 'NCeB0sxQmNor+c0u91ZEagcp9ygatL3PpOyVn90VZ3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}