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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cab094945e3deb2849c48c32f411ceceba3b134bef218119a72d2635d92b254b' 
  AND token = 'TiZPCK+e1OTH4M6/Wvo9h+Tkkc5otC3vyzMvcMHIh/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}