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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1b2e4146b8d9889448fc52caf5898698258f1cfedd4ef0b804012bd821c1389' 
  AND token = 'vLOKcdoxUvimoUMBxfe3KpS8jdh3MZGrT7QXN6xZePY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}