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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '134447d281c85fc7836fc19806f22e3d82eb5320d5abd85446d461d7b2ffe73c' 
  AND token = '+JO720unBPHIG1MF2WtXgtsit+6KvrmauuKqSke3eqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}