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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '145d1e03e2db9b9c5a27620eea816e2985f71b9f17b3f3d6dc7235449f005704' 
  AND token = 'z4xdmJy6k5XsIQ5TZmLy98XAcSX8H6fQ+f/rvpSA0DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}