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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '332a10ef1e9ef797e7fc05a2b7a11505cfac22e70691a1bdd73ea4d26ecbba29' 
  AND token = 'p4YsgSpf06h2saiS9kEW8mVhb3fkDyuiQ+VmLPBmytg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}