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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee9a7882208a5c8929df02f91be39d7b12a3e5d4902bb167b5db14c0a59c6477' 
  AND token = 'aCK5IpoS6GK1upSRcNdcvp5xBk4vE3UHuTpups5i1VM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}