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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1f9f9b0eca9b52fc263ee6b33df1b0473ee48bccc903433e0669594c9379aa8' 
  AND token = 'EwW+tQ++NKjqwjpxCVNmxxL1zrlfx3WsMDoSUWKbuy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}