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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422d20fda667a543cf65227f3105dc93d5ca9f4eee3f50524fb44713bd78aa87' 
  AND token = '185kKJcwu/1gGi3OmeMz13FvrRpzb/i53qpfIbZiha4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}