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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af1a380064d323812eb90d9c940522517b66bb5772ad9ff5d1aea83b1e8e98b8' 
  AND token = 'x2ErWuUOSE54lXhiNXVPLr95PSwwDSxuz9GVTZDVaIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}