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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a91ba0a7faf22ea4ed056b727f21aee52a91296afa7bb04b5361eea4f6e251d' 
  AND token = 'tPhwxZNrv+WtzdflFtC+MKV2rHC0b4g9+ASkWOhZV1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}