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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20f6bf5f7a8d508b1970317a50edcb666313e4e94324a4a682368685b378e82e' 
  AND token = 'S2xtGro2YGsjx7IndssBOUtF8o/FIyUHaie/zjQzcy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}