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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e70f2f670b287d8d5cd7e19f8137d8faac7268385e26c7eccff9ca36855c16cb' 
  AND token = 'C5GoPUlkikPo4tU20TN8I3rwUa1yRVVZlPcvP3iGpps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}