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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f94a6a0960b8719637ed646601acad8d7b5d04b1953dda1ccbf14aac93af0b4' 
  AND token = '50tfmymUVA9Q3olUAsvhbnFoA+eukTEhwQ0A4Om6Dy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}