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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745f1ea4ffb2d68e163802b07717ea4b5ad26fe3ceecec50f5b14988bb37837c' 
  AND token = 'KQfJ1avgP1VHn7mNWub5Z2fLXmg0nNgQ82FJJTh54Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}