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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c82f765420041d0800504b95e4f598aedf1cbf9e205fc50fdf39accdfcc912e9' 
  AND token = 'PO1OqvwJvFtVERoA9di7iLSpwpEJsj9+9t7Z1qHBEu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}