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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adef623a7b53871700f7121a1b00f2197188ea90fdb68ae6db855c2b1d277336' 
  AND token = 'DK7qfrhy5JOeWJbrVQqo/8DWz41m+wWzdJbr0zuqa2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}