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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ede4e9a62e020288c8caeb8c949abb772dfd87aaac61e51f96c18e7da0905c6' 
  AND token = '3v+VQC6s8fB4YyxFnesCkRPA93yI5V4VtwvcQPoP9EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}