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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e9273f7d807dab0e19446eae14791235990af67a2a250e063b5bf4a4c18439' 
  AND token = 'aNxSauxnUWvhBx/zTz1nXwR9KwxvxwYMmf7xQH6Rdu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}