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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c1453b5729eb5dd23149dfd5cdc4cec5e665b099d360c4aa018d2c0e15e8f03' 
  AND token = 'Z58nXlSC1nkXYuduPRhQ/W0wv1YiM8kCr5VYRDrdv3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}