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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7972abb6c6571f8ac0b729c535f28b090adf396b9b14eea1da2ca0f644586d7e' 
  AND token = 'ou/wrWeZ6jXG4MmaQS9l0fLfIM4QcMKEK23r78c2v4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}