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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1d31292226ef5098ddce9a5e7e7e4dfccf88f934240cb3959a76506d2de8a07' 
  AND token = 'byMt0nxar6/PF3k9Pyts8HBGgb6WJ8zk9/MDdTD1w2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}