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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d0668cc10e9e2b6c4d751eff6bb11cf76f5b947de788dcf62f2598a2c59fb9' 
  AND token = '4vRWVawUPBKX0Dl5Nji9o0OAtOdKbu71BcVyDzKEHdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}